A prostate biopsy collects small samples of prostate tissue so they can be examined under a microscope for cancer or other abnormalities. The procedure is usually recommended when a PSA blood test, prostate examination, MRI, or other finding raises concern. Using ultrasound and, in many cases, MRI information for guidance, the physician places a biopsy needle into selected areas of the prostate and removes several tiny tissue cores. The samples are then evaluated by a pathologist. If cancer is found, the biopsy provides information about the type and aggressiveness of the cells, helping your urologist discuss appropriate options such as surveillance, surgery, radiation, or other treatment.